D-glucose
 The
Glycolytic
Cycle
illustrated by L. Van Warren
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Mg2+
hexokinase
ATP
ADP
 
 DG10 = -4.0 kcal/mol
 
D-glucose-6-phosphate
Mg2+
or
Mn2+ 
phosphoglucoisomerase
DG10 = 0.4 kcal/mol
D-fructose-6-phosphate
Mg2+
phosphofructokinase
(6-phosphofructo-2-kinase shown)
 
ATP
ADP
 
DG10 = -4.0 kcal/mol
D-fructose-1,6-diphosphate
aldolase
 
 
 
 
 
 
 
 
 
DG10 = 5.73 kcal/mol
dihydroxyacetone
DG10 = 1.83 kcal/mol
glyceraldehyde-3-phosphate
trisephophate isomerase
glyceraldehyde-3-P dehydrogenase
 
NADH + H+
NAD+, Phosphate
 
DG10 = 1.5 kcal/mol
1,3-diphosphoglycerate
Mg2+
phosphoglycerate kinase
ATP
ADP
 
DG10 = -4.5 kcal/mol
3-phosphoglycerate
Mg2+
phosphoglycerate mutase
DG10 = 1.06 kcal/mol
2-phosphoglycerate
Mg2+
or
Mn2+ 
enolase
DG10 = 0.44 kcal/mol
2-phosphoenolpyruvate
Mg2+
and
K+ 
pyruvate kinase
 
ATP
ADP
 
DG10 = -7.5 kcal/mol
pyruvate
lactate dehydrogenase
 
NADH + H+
NAD+
 
DG10 = -6.0 kcal/mol
lactate
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Pathway Animation Copyright 1998: 
L. Van Warren
Warren Design Vision
All Rights Reserved
* - adapted from:
Organic Chemistry
by
Paula Yurkanis Bruice