Receptor World™

Neuroreceptors, Hormone Receptors, Bioenergetic Receptors, Etc.

-- click on receptor to see the full size image. --
The ligand for rhodopsin
is light:
E = hn


Rhodopsin Receptor Schematic

- after Fliesler et. al.
Rhodopsin is Vision

Receptors
are named
for their ligands
in many cases.

C - indicates a role in cancer.

thanks to:
G-Coupled Protein Receptor DB,
ChemFinder Web Server,
MDL and Viseur Service,

Structure Table © WDV
All Rights Reserved

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N e u r o t r a n s m i t t e r s   a n d   T h e i r   R e c e p t o r s

Histamine Ligand
histamine drawing

Histamine Properties

Dopamine Sites
dopamine drawing

Dopamine Properties

Histamine Receptor "Long Form"

Histamine R. "Short Form"

Dopamine R. "Long Form"

Dopamine Receptor "Short Form"

Serotonin Sites
serotonin drawing
Serotonin
one alpha helix

Neuropeptide Y

Clicking on a model
manipulates the model.

Clicking on the image
zooms the image.

Clicking on text
provides more information.


Serotonin Receptor "Long Form"

Serotonin R "Short Form"

Neuropeptide Y "Long Form"

Neuropeptide Y "Short Form"
serotonin drawing


Acetylcholine Properties  
serotonin drawing


Bradykinin Properties
   

Acetylcholine Receptor

Bradykinin Receptor
 
Galanin Receptor

Substance P Neurotransmitter

Substance K Neurotransmitter

Neurotensin Receptor

Neuromedin Receptor
C h e m o k i n e     R e c e p t o r s

Interleukin 8 Receptor C

Monocyte Attractant Receptor

Lymphocyte Directed Receptor

Eosinophil Attractant Receptor
In 1996 researchers found the mechanism for how chemokines, the messengers of the immune system block HIV: the virus enters cells via chemokine receptors. The chemokines, by binding to their receptors, can bar entry to HIV. Also in 1996, researchers reported the discovery of a genetic mutation in one of these chemokine receptors that slowed the progress of the disease or prevented infection.
R e p r o d u c t i v e   H o r m o n e s   &  R e c e p t o r s

Estrogen Receptor C


Progesterone Receptor C


Follicle Stimulating Hormone - FSH

Oxytocin

Lutropin Choriogonadotropic Hormone
Receptor

Gonadotropin Releasing Hormone
Receptor

FSH Receptor

Oxytocin Receptor

Prostaglandin Receptor *many types*

Prostacyclin Receptor

LPA Receptor 2 3 C
?

 Lysophosphatidic Acid Information
P i t u i t a r y ,  T h y r o i d ,  P a r a t h y r o i d  &   G r o w t h   H o r m o n e   R e c e p t o r s

Parathyroid Hormone Receptor

Thyrotropin Receptor

Thyrotropin Releasing Hormone
Receptor

PituitaryAdenylylCyclaseActivatingPeptide

Calcitonin Receptor

HGF Releasing Hormone Receptor

Growth Hormone Secretagogue
Receptor

Somatostatin (HGH) Receptor
 C a n c e r  I m p l i c a t e d   R e c e p t o r s

EpsteinBarrVirallyInduced Receptor C

MAS_ProtoOncogene Receptor C


Growth Hormone Receptor
 C 

 
A d r e n a l  H o r m o n e s   a n d   T h e i r   R e c e p t o r s

serotonin drawing

Adrenalin


Adrenalin Sites

Adreno-Release-CorticotropicHormone

CorticotropinReleasingFactor

Alpha Adrenalin "Short Form"

AlphaAdrenalin "Long Form"

Beta Adrenalin Receptor
 
B l o o d  P r e s s u r e  R e g u l a t o r y  H o r m o n e s  R e c e p t o r s

Vasopressin

Vasopressin Receptor

Angiotensin Receptor

Angiotensin
M o r e   R e c e p t o r s

EndothelinTypeBa

Throboxane

Bombesin Receptor
 
B i o e n e r g e t i c   R e c e p t o r s

Glucagon

Insulin

Click on the text under the receptor image to see more information.


Adenosine Receptor

Glucagon Receptor

zoom

Insulin Receptor

The insulin receptor does not share the 7 transmembrane spanning sequences of G Protein Coupled Receptors. It has only one transmembrane spanning sequence and is 1382 amino acids long.

 


NTP_Purine Receptor
 D i g e s t i v e  &  C l o t t i n g  C a s c a d e   R e c e p t o r s

Gastric Inhibitory Peptide Receptor

Proteinase Activated Receptor

Thrombin Receptor

Platelet Activating Factor Receptor

Orexin Hunger Neuropeptide

Vasoactive Intestinal Hormone Receptor

Secretin Hormone Receptor
 
 P h a r m a c o l o g i c a l l y  S i g n i f i c a n t   R e c e p t o r s

THC


THC Sites

Morphine Properties

Hydromorphone Properties

Cannabinoid Receptor Type 1

Cannabinoid Receptor Type 2

Mu Opioid Receptor

Kappa Opioid Receptor
  ?


Beta Endorphin 1 2
 

Delta Opioid Receptor

Opioid Receptor Type X

Metabotropic Glutamate Receptor G1

Metabotropic Glutamate Recep. G2

The Metabotropic Glutamate Receptors and Opioid Receptors are Involved In Related Pathways

  • ACTH STIMULATES THE ADRENAL GLANDS TO RELEASE CORTISOL.
  • MELANOCYTE-STIMULATING HORMONE INCREASES SKIN PIGMENTATION BY INCREASING MELANIN PRODUCTION IN MELANOCYTES.
  • BETA-ENDORPHIN AND MET-ENKEPHALIN ARE ENDOGENOUS OPIATES.
    ACTH AND MSH ARE PRODUCED BY THE PITUITARY GLAND.
  • SPECIFIC ENZYMATIC CLEAVAGES AT PAIRED BASIC RESIDUES YIELD THE DIFFERENT ACTIVE PEPTIDES.

Melanocyte Stimulating Hormone
Receptor

Melanocortin Receptor

Melatonin Receptor
 
M i s c .    R e c e p t o r s

Met-Leu-Phe Receptor

An Olfactory Receptor

EMA Receptor

Sphingosine-1-Phosphate Receptor

Latrotoxin Receptor

Anaphylatoxin Receptor

ExtracellularCalciumSensing
 

Smoothened Receptor

Frizzled Receptor

BonzoHuman Receptor

Ocular Albinism Protein Receptor