HCJ-SED | Pharmacokinetic, Pathway & Molecular Simulator

Medication & Regimen (Up to 4)

When Same Drug Is in Multiple Slots (Default = Superposition):

Multi-Step Titration Schedule (Slot 1):

Format: StartDay-EndDay:DoseMg (comma-separated)

■ Medication Slot 1 (Primary) Active

Dose (mg) Int (h) Start (h) Route

■ Medication Slot 2

Dose (mg) Int (h) Start (h) Route

■ Medication Slot 3

Dose (mg) Int (h) Start (h) Route

■ Medication Slot 4

Dose (mg) Int (h) Start (h) Route

Calendar Horizon (1–90 d) Cross-Taper Period (d) Solver Kinetics Renal / CYP2D6 & CYP3A4 Kinetics

Smart Auto-Horizon for Long Half-Life Drugs (Up to 90d) Discontinue at 50% Duration (Washout Curve) Round Cross-Taper Steps to Tablet Sizes

Blood & Reservoir Concentration Over Time

MEC–MTC Band Metab/RBC Overlap Dots

Horizon:

1–90d: 7 Days

Steady-State Final Cycle Telemetry: Inspect Curve:

Cycle Peak (Cmax)

Cycle Trough (Cmin)

Cycle Mean (Cmean)

Cycle Pop SD (Cstd σ)

Cycle Swing (ΔC)

Metab / RBC Mean

Parent 90% SS (3.32 t½)

Metab / RBC 90% SS

Hr:

Molecular Structure Viewer

Biochemical Pathway & Reservoirs

Click & drag or scroll to pan • Use 🔍+ / 🔍− or Shift+Wheel to zoom

Relative Potency vs. Morphine