"this" "is about" "p21 gene"
"OMIM 300237#TEXT" "is citation for" "this"
"TFIIS protein" "is a" "conserved eukaryotic transcription elongation factor"
"Human TFIIS" "is a kind of" "HUMAN TFIIS"
"Transcription Factor II S" "is a synonym for" "TFIIS"
"Human TFIIS" "contains a" "RNA polymerase II binding domain"
"Human TFIIS" "contains a" "zinc finger nucleic acid-binding domain"
"RNA polymerase II binding domain" "is required to stimulate" "transcription elongation"
"zinc finger domain" "is required to stimulate" "transcription elongation"
"zinc finger domain" "binds to" "nucleic acids"
"DNA" "is made of" "nucleic acids"
"Yeh" "identified in 1994" "p21 gene"
"Shatkin" "identified in 1994" "p21 gene"
"p21 gene" "codes for" "p21 protein"
"p21 protein" "belongs to" "SII family"
"p21 protein" "is predicted to have" "157 amino acids"
"p21 protein" "has a molecular mass of" "21 kD"
"p21 protein" "has an extremely basic pI of" "11.75"
"p21 protein" "is rich in" "arginine"
"p21 protein" "is rich in" "serine"
"p21 protein" "is rich in" "proline"
"p21 protein" "has at both ends" "nuclear localization signal"
"p21 protein" "is 29% identical to" "Human TFIIS"
"p21 protein" "is 29% identical to" "Mouse TFIIS"
"p21 protein" "lacks" "zinc finger domain"
"zinc finger domain" "is required in" "TFIIS"
"zinc finger domain" "is required for stimulation of" "transcription elongation"
"zinc finger domain" "is conserved" "between species"
"p21 protein" "contains" "zinc finger-like motif"
"p21 protein" "contains a related sequence to" "TFIIS Pol II binding region"
"Yeh" "made in 1994" "notation 1"
"Shatkin" "made in 1994" "notation 1"
"p21" "has an" "N-terminal region"
"N-terminal region" "contains an" "arginine/serine-rich region"
"arginine/serine-rich region" "is closely related to" "RS domain of SC35"
"SC35" "is a" "pre-mRNA splicing factor"
"p21 protein" "migrates on Western blots as a" "27 kD protein"
"p21" "has an" "N-terminal region"
"p21" "has an" "molecular mass of p21"
"the discrepancy" "has been noted by" "Yeh"
"the discrepancy" "has been noted by" "Shatkin"
"the discrepancy" "exists between the predicted and observed" "molecular mass of p21"
"the discrepancy" "could be due to" "the extremely basic nature of the protein"
"p21 protein" "is located in" "mammalian cell nucleus"
"p21 protein" "was studied in 1994 using" "immunofluorescence"
"the location of p21" "was found by in 1994 by" "Yeh"
"the location of p21" "was found by in 1994 by" "Shatkin"
"p21 protein" "when overexpressed modulates in a context-dependent fashion" "transcription"
"p21 protein" "when overexpressed increases" "c-fos promoter transcription"
"RSV LTR" "is a synonym for" "Rous sarcoma virus long terminal repeat"
"Rous sarcoma virus" "has a" "long terminal repeat"
"p21 protein" "when overexpressed represses" "RSV LTR promoter activity"
"RSV LTR" "has a" "RSV LTR promoter activity"
"RSV LTR function" "is" "promoter activity"
"zinc finger-like motif" "is necessary for inhibition of" "RSV LTR function"
"arginine/serine-rich region" "is necessary for inhibition of" "RSV LTR function"
"Yeh" "demonstrated in 1994 inhibition of" "RSV LTR function"
"Shatkin" "demonstrated in 1994 inhibition of" "RSV LTR function"
"RSV LTR promoter activity" "is inhibited at" "RNA level"
"RSV LTR promoter activity" "does not involve binding of" "p21 protein"
"p21 protein" "exerts its effects via protein-protein interactions with" "transcriptional regulators"
"Pillutla et al." "reported in 1999 the exon count of" "p21 gene"
"p21 gene" "contains" "3 exons"
"p21 gene" "has length of" "2.1 kb"
"TCEAL1" "is a synonym for" "p21 gene"
"TCEA-like 1" "is a synonym for" "p21 gene"
"p21 gene" "was analysed using" "Northern blot"
"p21 gene" "was expressed in all tissues as length" "1.2 kb mRNA"
"p21 gene" "was expressed in heart muscle as length" "7 kb mRNA"
"p21 gene" "was expressed in skeletal muscle as length" "7 kb mRNA"
"FISH" "is a synonym for" "fluorescence in situ hybridization"
"p21 gene" "was mapped using" "FISH"
"p21 gene" "has chromosomal location" "Xq22.1"
"Pillutla et al." "mapped chromosomal location of" "p21 gene"