9/21/99
Dr. Cooney
GeneBiochem
Summary Notes
L. Van Warren

Lecture 3:
DNA &
Chromosome
Structure

Questions

1) Q: List the absolutely essential functional elements of mammalian chromosomes.
   A1: According to page 766 of Lewin, Genes VI, the minimum features required for the existence of a chromosome are:

a) Telomeres to insure survival (prevent fraying of the ends).
b) A centromere to support segregation.
c) An origin to initiate replication.

   A2: According to the highlighted topics given in the first lecture. The essential elements are:

a) Telomeres
b) Centromeres
c) A replication origin.