Isoprenylated proteins |
|||
| protein | MW (kDA) |
Farnesyl (F) or geranylgeranyl (GG) |
C-terminal CaaX sequence |
| Lipid phosphatase | |||
| Type II inositol polyphosphate 5-phosphatase | 103 | GG | CNPL |
| Retinal enyzymes | |||
| Cyclic GMP phosphodiesterase alpha | 90 | F | CCIQ |
| Cyclic GMP phosphodiesterase beta | 88 | GG | CCIL |
| Rhodopsin kinase | 62 | F | CVLS |
| Nuclear lamins | |||
| Prelamin A | 74 | F | CSIM |
| Nuclear lamin B | 67 | F | CAIM |
| Peroxisomal protein | |||
| PxF | 39 | F | CLIM |
| Protein tyrosine phosphatases | |||
| PTPCAAX1/PRL-1 | 21 | F,GG | CCIQ |
| PTPCAAX2 | 21 | F,GG | CCVQ |
| Ras-like small GTP binding proteins | |||
| Rap 1A (k-rev 1) | 21 | GG | CQLL |
| Rho | 21 | GG | CLVL |
| Rac 1 | 24 | GG | CLLL |
| Rac 2 | 24 | GG | CSLL |
| G25K | 24 | GG | CVLL |
| Rab 1b | 22 | GG | GGCC |
| Rab 3a | 23 | GG | CAC |
| Rab 5 | 23 | GG | CCSN |
| Rap 2 | 21 | F | CNIQ |
| H-Ras | 21 | F | CVLS |
| K-Ras | 21 | F | CVIM |
| N-Ras | 21 | F | CVVM |
| Heterotrimeric G proteins | |||
| Transducin | 6 | F | CVIS |
| Brain G Beta-gamma | 6 | GG | CAIL |