"this"
"is about" "BRCA1 gene"
"Nature 1997
Sep 11;389(6647):187-90" "is citation for" "this"
"this"
"authored by" "Somasundaram K"
"this" "authored by" "Zhang H"
"this" "authored by" "Zeng YX"
"this" "authored by" "Houvras Y"
"this" "authored by" "Peng Y"
"this" "authored by" "Zhang H"
"this" "authored by" "Wu GS"
"this" "authored by" "Licht JD"
"this" "authored by" "Weber BL"
"this" "authored by" "El-Deiry WS"
"this"
"authored at" "Laboratory
of Molecular Oncology and Cell
Cycle Regulation"
"this" "authored at" "Howard Hughes Medical Institute"
"this" "authored at" "Department of Medicine"
"this" "authored at" "University of Pennsylvania"
"this" "authored at" "School of Medicine"
"this" "authored at" "Philadelphia"
"this"
"authored at" "19104"
"this"
"authored at" "USA"
"hereditary
breast cancer" "is a kind of" "breast cancer"
"mutated
BRCA1 protein" "is a kind of" "BRCA1 protein"
"mutated
BRCA1 gene" "is a kind of" "BRCA1 gene"
"BRCA1
mutated gene" "causes" "BRCA1 mutated protein"
"mutated
BRCA1 protein" "causes" "hereditary breast cancer"
"mutated
BRCA1 protein" "causes" "hereditary ovarian cancer"
"BRCA1
protein" "is found in" "the cell nucleus"
"BRCA1
protein" "is a" "transcription factor"
"BRCA1
protein" "interacts with" "RAD51 protein"
"RAD51
protein" "is a" "recombination protein"
"RAD51
protein" "is a" "repair protein"
"mutated
BRCA1 gene" "causes 100-fold higher rates of breast cancer in"
"young women"
"missing
BRCA1 protein" "kills mice before" "day 8"
"BRCA1
protein" "regulates" "cell growth"
"BRCA1
protein" "causes expression of" "p21 protein"
"p21
protein" "inhibits" "cyclin-dependent kinases"
"p21
protein" "is also known as" "p21WAF1/CIP1"
"BRCA1
protein" "inhibits S-phase cell-cycle progression in" "human
cancer cells"
"BRCA1
protein" "does not inhibit S-phase cell-cycle progression in"
"p21-/- cells"
"BRCA1
protein" "does inhibit S-phase cell-cycle progression in" "p21+/+
cells"
"S-phase"
"is a phase" of "cell cycle"
"S-phase"
"is a synonym" for "DNA synthesis phase"
"cell
cycle" "is a property of" "human cancer cells"
"BRCA1
mutant protein" "does not inhibit S-phase in" "human cancer
cells"
"BCTumorCells"
"are a kind of" "human cancer cell"
"BRCA1
protein" "induces" "p21 protein"
"p21
protein" "stops" "cell cycle"
"cell
cycle" "is a property of" "normal cells"
"p21
protein" "stops" "cell growth"
"cell
growth" "is a property of" "cell"