relation("Nature 1997 Sep 11;389(6647):187-90", "is citation for", "this");
relation("this", "authored by", "Somasundaram K");
relation("this", "authored by", "Zhang H");
relation("this", "authored by", "Zeng YX");
relation("this", "authored by", "Houvras Y");
relation("this", "authored by", "Peng Y");
relation("this", "authored by", "Zhang H");
relation("this", "authored by", "Wu GS");
relation("this", "authored by", "Licht JD");
relation("this", "authored by", "Weber BL");
relation("this", "authored by", "El-Deiry WS");
relation("this", "authored at", "Laboratory of Molecular Oncology and Cell Cycle Regulation");
relation("this", "authored at", "Howard Hughes Medical Institute");
relation("this", "authored at", "Department of Medicine");
relation("this", "authored at", "University of Pennsylvania");
relation("this", "authored at", "School of Medicine");
relation("this", "authored at", "Philadelphia");
relation("this", "authored at", "19104" );
relation("this", "authored at", "USA");
relation("hereditary breast cancer", "is a kind of", "breast cancer");
relation("mutated BRCA1 protein", "is a kind of", "BRCA1 protein");
relation("mutated BRCA1 gene", "is a kind of", "BRCA1 gene");
relation("BRCA1 mutated gene", "causes", "BRCA1 mutated protein");
relation("mutated BRCA1 protein", "causes", "hereditary breast cancer");
relation("mutated BRCA1 protein", "causes", "hereditary ovarian cancer");
relation("BRCA1 protein", "is found in", "the cell nucleus");
relation("BRCA1 protein", "is a", "transcription factor");
relation("BRCA1 protein", "interacts with", "RAD51 protein");
relation("RAD51 protein", "is a", "recombination protein");
relation("RAD51 protein", "is a", "repair protein");
relation("mutated BRCA1 gene", "causes 100-fold higher rates of breast cancer in", "young women" );
relation("missing BRCA1 protein", "kills mice before", "day 8");
relation("BRCA1 protein", "regulates", "cell growth");
relation("BRCA1 protein", "causes expression of", "p21 protein");
relation("p21 protein", "inhibits", "cyclin-dependent kinases");
relation("p21 protein", "is also known as", "p21WAF1/CIP1");
relation("BRCA1 protein", "inhibits S-phase cell-cycle progression in", "human cancer cells");
relation("BRCA1 protein", "does not inhibit S-phase cell-cycle progression in", "p21-/- cells");
relation("BRCA1 protein", "does inhibit S-phase cell-cycle progression in", "p21+/+ cells");
relation("S-phase", "is a phase" of "cell cycle");
relation("S-phase", "is a synonym" for "DNA synthesis phase");
relation("cell cycle", "is a property of", "human cancer cells");
relation("BRCA1 mutant protein", "does not inhibit S-phase in", "human cancer cells");
relation("BCTumorCells", "are a kind of", "human cancer cell");
relation("BRCA1 protein", "induces", "p21 protein");
relation("p21 protein", "stops", "cell cycle");
relation("cell cycle", "is a property of", "normal cells");
relation("p21 protein", "stops", "cell growth");
relation("cell growth", "is a property of", "cell");