"this" "is about" "PI3K protein"
"BCR receptor" "is a synonym for" "B Cell receptor"
"PI3K protein" "produces" "PI3K protein-derived lipids"
"pleckstrin homology domain-containing proteins" "is a synonym for" "Pleckstrin proteins"
"PI3K protein-derived lipids" "recruit" "Pleckstrin proteins"
"Pleckstrin proteins" "are recruited to" "plasma membrane"
"Akt protein" "is" "a kinase"
"BCR receptor" "activates" "Akt protein"
"Akt protein" "phosphorylates" "transcription factors"
"Akt protein" "phosphorylates" "proteins"
"glycogen synthase kinase-3" "is a synonym for" "GSK-3 protein"
"Akt protein" "regulates" "GSK-3 protein"
"GSK-3 protein" "is a" "kinase"
"(NF-AT)c1" "is a synonym for" "NFAT protein"
"nuclear factor of activated T cells" "is a synonym for" "NFAT protein"
"NFAT protein" "is a substrate of" "GSK-3 protein"
"[beta]-catenin transcriptional activators" "is a synonym for" "BCTA protein"
"BCTA protein" "is a substrate of" "GSK-3 protein"
"PI3K protein-derived lipids" "regulate signaling of" "BCR targets"
"PI3K protein-derived lipids" "regulate localization" "BCR targets"
"BCR receptor" "is involved in" "BCR signaling"
"BCR receptor" "is involved in" "BCR targets"
"PI3K protein" "is recruited in" "BCR signaling"
"PI3K protein" "is recruited to" "plasma membrane"
"PI3K protein substrates" "are located in" "plasma membrane"
"PI3K protein" "is homologous" "Src protein"
"SH2 domains" "is a synonym for" "Src homology 2 domains"
"PI3K protein" "contains" "SH2 domains"
"PI3K protein" "contains" "SH2 domains"
"SH2 domains" "bind to" "phosphotyrosine-containing sequences"
"phosphotyrosine-containing sequences" "are on" "membrane-associated docking protein"
"docking protein" "are on" "plasma membrane"
"BCR receptor" "recruits with" "docking protein"
"docking protein" "recruit" "PI3K protein"
"CD19 protein" "is" "docking protein"
"Cbl protein" "is" "docking protein"
"Gab1 protein" "is" "docking protein"
"Gab2 protein" "may be" "docking protein"
"Gab1 protein" "colocalizes" "PI3K protein"
"SHIP protein" "contains" "SH2 domains"
"Gab1 protein" "is colocalized with" "SHIP protein"
"Gab1 protein" "is colocalized with" "SHP2 protein"
"SHP2 protein" "is an" "enzyme"
"SHIP protein" "is an" "enzyme"
"SHP2 protein" "regulates signaling of" "PI3K protein"
"SHIP protein" "regulates signaling of" "PI3K protein"
"Rap1 protein" "is a" "GTPase"
"BCR protein" "activates" "Rap1 protein"
"Rap1 protein" "is activated by" "diacylglycerol"
"diacylglycerol" "is produced by" "phospholipase C protein"
"phospholipase C protein" "is an" "enzyme"
"Rap1 protein" "appears to regulate" "cell adhesion"
"Rap1 protein" "appears to regulate" "cell polarity"
"Rap1 protein" "appears to regulate" "B-cell migration"